Hepatocellular carcinoma is prevalent in males and a significant cause of mortality by cancer. The most of diagnoses occur in the low- and lower-middle-income countries. The etiopathogenesis is associated with chronic viral hepatitis, alcoholism, steatohepatitis, tobacco smoking, aflatoxin exposure, iron overload, or large cell dysplasia. The incidence and mortality rate increased in the last decades. More common sites of metastases are lungs, lymph nodes, central nervous system, and bones. The tumor subtypes include fibrolamellar, scirrhous, spindle cell, clear cell, and pleomorphic; the sarcomatous type is rare and present pleomorphic and spindle and cells. We report the autopsy data of a 73-year-old male presenting a unsuspected sarcomatoid hepatocellular carcinoma, confirmed by elevated serum levels of CEA and alpha-fetoprotein, positivity for hepatocyte specific antigens, and classical histopathologic pattern.
Keywords: Autopsy; Diagnosis; Hepatocellular carcinoma: Sarcomatoid
