Cardiac amyloidosis: a challenging diagnosis

Autopsy And Case Reports

Av. Prof. Lineu Prestes, 2565
São Paulo / SP
Telefone: (11) 3091-9448
ISSN: 22361960
Editor Chefe: Maria Claudia Nogueira Zerbini
Início Publicação: 28/02/2011
Periodicidade: Trimestral
Área de Estudo: Medicina

Cardiac amyloidosis: a challenging diagnosis

Ano: 2014 | Volume: 4 | Número: 4
Autores: G. C. P. Morais, M. M. Arruda, J. C. A. Bonadia, G. Pozzan
Autor Correspondente: M. M. Arruda | [email protected]

Palavras-chave: amyloidosis, cardiomyopathy restrictive, autopsy

Resumos Cadastrados

Resumo Inglês:

Cardiovascular involvement of amyloidosis is present in 90% of cases, which is frequently associated with the primary form of the disease (AL amyloidosis). Clinical manifestations are represented by heart failure due to restrictive myocardiopathy and electrical impulse conduction abnormalities, which are clinically remarkable in up to 50% of the cases. The prognosis of patients with systemic amyloidosis is directly associated with the presence of cardiac involvement, such that survival does not usually exceed 4 months after the onset of heart failure signs and symptoms. The authors report a case of primary systemic amyloidosis, diagnosed only at autopsy, with severe cardiac involvement.