This research aimed to identify facilitators and restrictive factors on Technological Transfer by comparing case studies of the Brazilian Technology Transfer Offices (TTO). The research was carried by a comparative case studies based on interviews with Directors and selected documentation. The three case studies’ results revealed, regarding the restrictive factors, that the federal universities showed an initial cooperation process through their TTO, whereas the state university presented facilitator factors about better-structured cooperative processes and generated returns to the institution. Federal universities showed restrictive factors from a legal framework and changeable professors’ profile and personal interests more dedicated to research and lectures in graduate courses than I-U partnerships. This research evidences the importance of national policies towards technology transfer via industry-university in developing countries.
