The aim of this work was to study the effect of tobacco (Nicotiana tobaccum) leaf dust at sublethal concentrations
(375.6, 187.8, 93.9 0.0mg/L) on biochemical parameters of Hybrid catfish in a static semi-renewable bioassay
system with the aim to ascertain its effect on the test fish after 14 days exposure period. The effects of the plant dust
on the test fish was dose-dependent, revealing significant difference in albumin, glucose, triglyceride, cholesterol,
urea, and uric acid of the serum, liver and kidney; total protein and globulin of serum and kidney and creatinine
and calcium of the serum while insignificant difference were observed for calcium and creatinine in liver and kidney
and total protein and globulin in liver compared to the control. The effect of the plant dust was most pronounced in
the serum, less in the kidney and least in the liver. However, the monitored water quality parameters revealed that
the plant dust had effects on primary productivity, thus the biodiversity of organisms.
