In this edition, we would like to highlight the article Möbius Syndrome (MS): Misoprostol Use and Speech and Language Characteristics. This study aims to verify speech and language performance of children with MS whose mothers reported use of misoprostol (Cytotec, Pfizer, Connecticut, United States) compared with children with MS from mothers who did not report use. The sample of this study consisted of 18 girls and boys with a previous diagnosis of MS, aged from 4 months to 10 years. The stomatognathic system beyond receptive and expressive language and speech was evaluated in children with MS, and their mothers were questioned whether they used misoprostol during the pregnancy or not. From the total, 61.1% admitted taking the drug Cytotec at some time during pregnancy, usually in the first few weeks. The researchers concluded that there was a large contingent of women who took misoprostol without knowing its teratogenic action. Moreover, the lack of facial expressions and speech disorders were common characteristics of the individuals with MS, whether the mothers took misoprostol during the pregnancy or not.