An interesting case of subacute combined degeneration

Revista de Medicina da UFC

Gerência de Ensino e Pesquisa - Universidade Federal do Ceará/Rua Coronel Nunes de Melo, S/N - Bloco dos ambulatórios (ilhas) - Andar superior - Rodolfo Teófilo
Fortaleza / CE
Telefone: (85) 3366-8590
ISSN: 24476595
Editor Chefe: Renan Magalhães Montenegro Júnior
Início Publicação: 30/11/2014
Periodicidade: Trimestral
Área de Estudo: Medicina

An interesting case of subacute combined degeneration

Ano: 2022 | Volume: 62 | Número: 1
Autores: Italo Gustavo Lima Monteiro, Gabriela Studart Galdino
Autor Correspondente: Italo Gustavo Lima Monteiro | [email protected]

Palavras-chave: Anemia, Subacute combined degenerarion, Vitamin B12 deficiency, Neuropathy, Myelopathy

Resumos Cadastrados

Resumo Inglês:

A 41-year-old man presented with history of paresthesia, weakness in the legs to the point of not being able to walk, constipation and urinary retention for the last 6 months. For the previous 18 months he got deep depressed and lost 36kg after his wife died of breast cancer. Physical examination was marked by psychomotor slowing, paresis over four members, especially legs, a sensitive level on T11 and impairment of proprioception. Laboratory analysis revealed pancytopenia, macrocytosis low vitamin B12 level and high homocysteine. He had no diet restrictions. Tests for syphilis were negative. Serology for celiac disease and antibody to intrinsic factor and parietal cells were negative.