Introduction: Although chronic diseases are prevalent in geriatrics, sexually transmitted diseases have been prominent, such as human immunodeficiency virus (HIV) infection. The study aims to relate the polytherapy used in these patients with drug interaction.
Methods: A literature review about the subject was conducted from the databases: Scientific Electronic Library Online and Scientific & Academic Publishing and US National Library of Medicine National Institutes of Health
Results And Discussion: Antiretroviral Therapy (ART) by itself includes 3 drugs and may be escorted by drugs for comorbidities resulting in polypharmacyrisk and interactions related to increased therapeutic potential. In the elderly the drug-drug interaction may reach 51% and each drug increases the risk of adverse effects by 10%
Conclusion: The risk and benefit of drug use in the elderly is tenuous. Thus, medical education should be promoted regarding the risk of polypharmacy, especially in geriatric patients.
