Prevalence of Microorganisms and Immunoglobulins in Children with Tonsillar Hypertrophy and Adenoiditis

International Archives of Otorhinolaryngology

Rua Teodoro Sampaio, 483, Pinheiros
São Paulo / SP
Telefone: (11)3068-9855
ISSN: 18099777
Editor Chefe: Geraldo Pereira Jotz
Início Publicação: 31/12/2009
Periodicidade: Trimestral
Área de Estudo: Medicina

Prevalence of Microorganisms and Immunoglobulins in Children with Tonsillar Hypertrophy and Adenoiditis

Ano: 2014 | Volume: 18 | Número: 3
Autores: Henrique Prestes Miramontes, Djalma José Fagundes, Julia Coelho Lima e Jurgielewicz, Haroldo Prestes Miramontes Neto, Renan Gianotto de Oliveira, Gustavo Gianotto de Oliveira, Maria Rosa Machado de Souza
Autor Correspondente: Henrique Prestes Miramontes | [email protected]

Palavras-chave: child, tonsillectomy, immunoglobulins, immune system

Resumos Cadastrados

Resumo Inglês:

Introduction: Benign idiopathic tonsillar hypertrophy (HBI) may affect a child's quality of life and sleep. Several studies have sought to relate the clinical features of HBI with the infectious and/or immunologic changes that occur.

Objective: To increase the knowledge of the etiology of HBI.

Data Synthesis: From 2012 to 2013 we conducted a retrospective observational study of 101 children with HBI who underwent tonsillectomies at Ambulatory ENT General Hospital of the East Zone of São Paulo City, a region with a poor socioeconomic population. Preoperative serologic results were available to confirm mononucleosis, cytomegalovirus, anti-streptolysin O (ASLO) and immunoglobulins. The mean patient age was 5.8 years (55% male, 45% female). Using the Mann-Whitney U test, we identified significant gender differences in the parameters of immunoglobulins (Ig) M (IgM), IgA, and IgE. Forty-seven percent of the patients had increased ASLO levels, and 37% had increased IgE levels.

Conclusion: An evaluation of a patient's serologic parameters and laboratory results may be relevant to the etiology and prevention of HBI. Based on the results obtained from the study sample, the identification of etiologic agents and causative factors remain a public health challenge that affects the quality of life of children.