Psycho-emotional stress - A cause of coronary artery disease
Acta Scientiae Veterinariae
Psycho-emotional stress - A cause of coronary artery disease
Autor Correspondente: Victor G Rajamanickam | [email protected]
Palavras-chave: lipid profile, oxidative stress, hung stress, rabbit, lipid peroxidation
Resumos Cadastrados
Resumo Inglês:
Psycho-emotional stress is one of the risk factors for metabolic syndrome and related diseases. Hence, this study has
designed to the effect of psycho-emotional stress in the form of immobilization stress in rabbits. In this study, we used 12 male
New Zealand White rabbits (2.5 -3 kg body weight), Six animals for hanging fixation and another six as control. Blood samples
were taken before hanging (0 minute) and at 60, 120 minutes. Serum was separated and used for the estimation of various
biochemical parameters. Hanging fixation appears to produce significant increase in malondialdehyde and lipid profile levels.
The non-enzymatic antioxidants like reduced glutathione, vitamin E and ceruloplasmin were found to be decrease and the level
of enzymatic antioxidant like glutathione peroxidase was increased significantly. The results reveal that the hanging fixation
may develop coronary artery disease. This is the area, which should be evaluated further by carrying out chronic studies in hung
stress and by histopathological studies.
