Vitamin B12 deficiency: metabolic effects, clinical evaluation, and treatment
Revista de Medicina da UFC
Endereço:
Gerência de Ensino e Pesquisa - Universidade Federal do Ceará/Rua Coronel Nunes de Melo, S/N - Bloco dos ambulatórios (ilhas) - Andar superior - Rodolfo Teófilo
Fortaleza / CE
60430-270
Site: http://periodicos.ufc.br/revistademedicinadaufc
Telefone: (85) 3366-8590
ISSN: 24476595
Editor Chefe: Renan Magalhães Montenegro Júnior
Início Publicação: 30/11/2014
Periodicidade: Trimestral
Área de Estudo: Medicina
Vitamin B12 deficiency: metabolic effects, clinical evaluation, and treatment
Ano: 2019 | Volume: 59 | Número: 2
Autores: Synara Cavalcante Lopes, Daniel Duarte Gadelha, Manuela Dias de Carvalho, Virgínia Fernandes de Oliveira, Renan Magalhães Montenegro Junior
Autor Correspondente: Synara Cavalcante Lopes | [email protected]
Autor Correspondente: Synara Cavalcante Lopes | [email protected]
Palavras-chave: Vitamin B12; Vitamin B12 deficiency; Methylmalonic acid; Metabolic diseases; Metabolic syndrome; Diabetes
Resumos Cadastrados
Resumo Português:
Vitamin B12 is a water-soluble essential micronutrient, required by all the body cells. Its deficiency has been implicated not only in hematological and neurological disorders, but also in many metabolic processes, such as insulin resistance and body composition changes, which have aroused particular interest in recent years. This study reviews the physiology of vitamin B12 from its digestion and absorption to its distribution in tissues, metabolic effects and controversies regarding the diagnosis of deficiency, and to dietary and pharmacological treatments.
