The water quality of a river basin dependent on numerous factors, whether natural or anthropogenic. Thus, this research aims to analyze the water quality parameters and the influence of land use and land cover in the watershed of Abaúna Rio, Brazil. The methodology made it possible to analyze the aquatic and terrestrial environment so as to achieve integration between the different uses and land cover and water parameters. For this, we used the satellite image Landsat 8, for that survey land use and land cover. The water parameters were: total suspended solids (TSS), water temperature (Temp.); hydrogen potential (pH); dissolved oxygen (DO), turbidity and total coliforms. From the integrated assessment of aquatic and terrestrial environment, it was found that water most collection points falls within the rules of CONAMA, but not for human consumption and it became clear that the uses are not in accordance with the rules of Federal Forest code. Therefore, the uses are interfering in water quality by altering the physical, chemical and bacteriological. For the improvement of the entire watershed water quality it is important to implement the use of alternative and land cover for the preservation and restoration of riparian forest.