Introdução: O carcinoma epidermoide na cabeça e pescoço é diagnosticado em aproximadamente 40% dos casos
em estádios clÃnicos avançados.
Objetivo: Avaliar a sobrevida livre de doença nos pacientes com carcinoma epidermoide de orofaringe de
estádio clÃnico (EC) precoce (I e II), submetidos ao tratamento cirúrgico ou quimioradioterápico.
Método: Estudo retrospectivo de 139 prontuários de pacientes portadores de carcinoma epidermoide de orofaringe
submetidos a tratamento com intenção curativa, sendo elegÃveis 38 casos de tumores de estádios
clÃnicos precoces (I e II). Destes, 27 (71,1%) foram à cirurgia e 11 (28,9%) à quimioradioterapia, com
idade média de 56,4 anos. Quanto ao gênero, 31 (81,6%) eram do masculino e sete (18,4%) do feminino.
Resultados: Nos 11 pacientes submetidos à quimioradioterapia, 72,7% obtiveram controle loco-regional da doença
e a sobrevida livre de doença há dois anos foram 42%. Dentre os 27 pacientes operados, 19 mantiveram-
se em EC I e II no laudo histológico e seis foram à radioterapia pós-operatória. A sobrevida
livre de doença há dois anos foi 70%.
Conclusão: Os pacientes submetidos inicialmente à cirurgia tiveram melhor sobrevida livre de doença, quando
comparados aos pacientes com tratamento quimioradioterápico.
Introduction: The epidermoid carcinoma of the upper aerodigestive tract is diagnosed in approximately 40% of the
cases of advanced clinical stages.
Objective: To evaluate the disease-free interval in patients with clinical stages I and II epidermoid carcinoma who
were submitted to surgery or chemoradiation.
Method: Retrospective study of the records of 139 patients treated for oropharyngeal epidermoid carcinoma
submitted to treatment with curative intent. Among those patients, 38 were classified with early tumors
clinical stages I and II. Twenty-seven (71.1%) underwent surgical treatment whereas eleven (28.9%)
were treated with chemoradiation. The mean age was 56.4 years; 31 cases (81.6%) were in men and
seven (18.4%) were in women.
Results: Among the eleven patients who were submitted to chemoradiation, 72.7% obtained locoregional control
of the disease and their disease-free survival was of 42%. Among the 27 patients operated, 19 remained
in Clinical Stages I and II in the histological report and six underwent postoperative radiation therapy.
The disease-free interval for two years was of 70%.
Conclusion: The patients submitted to the surgery had a better disease-free interval as compared to those submitted
to chemoradiation treatment.
