We read a recent case series with a review on disseminated herpes zoster (HZ) occurring associated with the COVID-19 vaccination.1 Pathophysiological mechanisms were aging, and diseases or treatments causing low cell-mediated immunity; but HZ may occur in 15% of immunocompetent.1 An 79-year-old male informed his antecedent of varicella but no previous HZ episode; worthy of note, he was using prednisolone, antihistamines, pramipexole and levodopa. Four days after the first dose of the Oxford-AstraZeneca COVID-19 vaccine on the left arm, he developed vesicles distributed along the C7, C8, and T1 ipsilateral dermatomes.