Two cases of relapse in borderline leprosy were reported. Despite the late-reversal, reaction-like feature, the suspicion of relapse
in both was based on persistent and slow-developing skin lesions and an absence of acute neuritis or reaction during one year of
follow-up. The authors have considered this possible occurrence in lepromatous borderline-treated patients after their immune cellular
restoration and defend that not all Type 1 reactions would be an inflammatory answer to persistent Mycobacterium leprae, but that
they could be. Therefore, a relapse diagnosis could be applied and it is more advisable, as one year of Multi-Drug Therapy (MDT) is
less dangerous and more efficient for these cases than one year of corticosteroids.
