Diagnosis of malignancy in the vermiform appendix is quite rare. The most
common histological malignant neoplasia found in this tiny portion of the
gastrointestinal tract is represented by the mucinous adenocarcinoma. This
entity predominates in males around 50 years of age, and clinical presentation
usually mimics or occurs along with an acute appendicitis. Early diagnosis is
outside the rule since most cases at this stage are symptomless. The authors
present the case of a 59-year-old female patient who looked for medical
attention complaining of abdominal pain. Physical examination and laboratory
workup were poor in diagnostic findings. The computed tomography images
were compatible with the diagnosis of appendicitis and/or appendiceal
neoplasia. The patient underwent a laparotomy and right hemicolectomy.
The histological examination disclosed a moderately differentiated mucinous
adenocarcinoma of the appendix stage T4a, N0, M0. The patient outcome
was uneventful and was referred to an oncological center.