Juvenile nasopharyngeal angiofibroma (JNA) is a rare benign lesion, which is highly vascular and local invasive, and occurs almost exclusively in young males. The treatment of choice is surgery, but embolization may be considered to reduce bleeding and surgical time. Endoscopic resection is an alternative approach to open procedures associated with reduced morbidity. This study aims at reporting the preoperative and intraoperative management of JNA at our institution. The patient was subjected to clinical examination with nasal endoscopy, ophthalmologic evaluation, magnetic resonance imaging (MRI)/computed tomography (CT) and finally endoscopic surgery with preoperative embolization as a treatment option. Intra-operative blood loss was excessive and a blood transfusion was required.